Chemistry and measurement Reviewed August 16, 2026

Caryophyllene Oxide Terpene

Caryophyllene oxide • carry-OFF-ill-een OK-side • /ˌkæriˈɒfɪliːn ˈɒksaɪd/

An oxygenated relative of beta-caryophyllene measured separately.

Chemical class: Oxygenated sesquiterpene
Common aroma notes: dry wood, spice, herbal
COA names: Caryophyllene Oxide

Identity and cannabis context

What Caryophyllene Oxide is

Caryophyllene oxide may form through oxidation and appears separately on some panels.

Aroma vocabulary

People commonly describe isolated caryophyllene oxide with dry wood, spice, herbal notes. A finished flower or extract contains a more complex volatile mixture.

Also found in

clove
rosemary

Chemistry and measurement

What the evidence actually shows

The compound is included in regulated testing and analytical methods.

Finding 1

chemistry

Caryophyllene oxide is analytically distinct from beta-caryophyllene.

Limit: Presence may reflect plant production, processing, or oxidation.

Sources: Office of Cannabis Management Testing Limits (opens in new tab); Simultaneous quantification of terpenes and cannabinoids by reversed-phase LC-APCI-MS/MS in Cannabis sativa L. samples combined with a subsequent chemometric analysis (opens in new tab)

What we do not know

Beta-caryophyllene evidence cannot automatically be assigned to its oxide, and consumer benefits are unestablished.

Safety and interpretation

A certificate of analysis identifies composition, not a safe or effective dose. Inhalation can irritate airways, and heating terpenes can create degradation products.

This page is educational and does not provide medical advice. Route, dose, oxidation, heat, other ingredients, and individual health conditions all change risk.

Database records listing Caryophyllene Oxide

This bounded preview shows records whose available profile contains Caryophyllene Oxide. It is not a total, a dominant-terpene ranking, or a guarantee about a current retail batch.

Relaxing High

Pineapple Express

Pineapple Express is a sativa-leaning hybrid (Trainwreck x Hawaiian) known for its sweet pineapple-and-citrus flavor and clear-headed, energetic high. Myrcene and caryophyllene dominate its terpene profile, delivering euphoric, creative, and uplifted effects balanced by gentle relaxation. A go-to daytime strain for stress relief, focus, and mood elevation, with THC typically between 17-26%.

Myrcene-dominant Euphoric Uplifted

Hybrid

Uplifting High

Lemon Cherry Gelato

Lemon Cherry Gelato is a potent, Limonene-forward hybrid from Sunset Sherbet and Girl Scout Cookies genetics, delivering bright citrus-cherry flavor and a two-phase high: uplifting, talkative euphoria up front that settles into relaxed, sleepy comfort. Bred by Backpackboyz, this award-winning cut (High Times Cannabis Cup) tests as high as 33% THC and appeals to those chasing flavor-forward flower with genuine versatility for social nights or unwinding evenings.

Limonene-dominant Uplifted Euphoric

Hybrid

Relaxing High

Purple Kush

Purple Kush is a legendary 100% pure indica from Oakland, California, bred from Hindu Kush and Purple Afghani. Expect sweet grape and berry flavors, earthy-spicy aromas, and a deeply relaxing, sleepy euphoria backed by myrcene and linalool. With THC reaching up to 27%, it's a potent nighttime companion prized for easing stress, pain, and insomnia.

Myrcene-dominant Relaxed Sleepy

Indica

Relaxing High

Cannatonic

Cannatonic is a balanced 50/50 hybrid bred by Resin Seeds from MK Ultra and G13 Haze, famous for pioneering high-CBD, low-THC genetics. Expect a relaxed, clear-headed, and functional high paired with earthy, citrus, and pine flavors. Its myrcene-driven terpene profile supports calm focus rather than heavy sedation, making it a go-to choice for daytime stress relief, mild pain management, and productive relaxation without overwhelming psychoactivity.

Myrcene-dominant Relaxed Focused

Hybrid

Energetic High

Pink Boost Goddess

Pink Boost Goddess (PBG) is a decorated sativa-dominant hybrid (70/30) from Emerald Spirit Botanicals, crossing Black Garlic, Boost, and Goddess OG. Myrcene, terpinolene, and ocimene combine for a berry-mint aroma and a clear, uplifted, focused high. Prized for its unique terpene and cannabinoid chemistry, it's collected dozens of Emerald Cup and California State Fair awards, making it a top pick for daytime creativity, social energy, and productive focus.

Myrcene-dominant Uplifted Focused

Hybrid

Uplifting High

Peanut Butter Breath

Peanut Butter Breath is a 50/50 hybrid from ThugPug Genetics, crossing Do-Si-Dos with Mendo Breath F2. Limonene-dominant terpenes deliver a nutty, earthy, buttery flavor with citrus and spicy diesel undertones. Effects move from euphoric and creative to deeply relaxed and sleepy, making it a favorite evening strain for unwinding, easing stress, and supporting sleep. THC can reach up to 30%, so it suits more experienced consumers.

Limonene-dominant Relaxed Euphoric

Hybrid

Balancing High

Grape Gasoline

Grape Gasoline is a balanced 50/50 hybrid from Compound Genetics, crossing Grape Pie with Jet Fuel Gelato. Expect a loud grape-and-diesel nose, caryophyllene-driven spice, and an effect profile that swings from relaxed and euphoric to uplifted and creative. With THC reaching up to 31%, it's a versatile evening strain suited for stress relief, pain management, and easy social unwinding.

Caryophyllene-dominant Relaxed Euphoric

Hybrid

Relieving High

Banana Cream Cake

Banana Cream Cake (BCC) is a 70/30 Indica-leaning hybrid from Seed Junky Genetics, blending Wedding Cake, Banana OG, and related dessert-strain genetics. Dominant caryophyllene delivers a spicy backbone beneath sweet, tropical, vanilla flavors. Effects run relaxed, happy, euphoric, and creative — a versatile evening strain with award-winning pedigree and THC ranging from 15% to nearly 30%.

Caryophyllene-dominant Relaxed Uplifted

Hybrid

Sources

Office of Cannabis Management Testing Limits (opens in new tab)
New York State Office of Cannabis Management, 2026 • chemistry
Simultaneous quantification of terpenes and cannabinoids by reversed-phase LC-APCI-MS/MS in Cannabis sativa L. samples combined with a subsequent chemometric analysis (opens in new tab)
Analytical and Bioanalytical Chemistry, 2024 • chemistry

Related terpene profiles

Caryophyllene Oxide questions

What is Caryophyllene Oxide?

Caryophyllene Oxide (Caryophyllene oxide) is an oxygenated relative of beta-caryophyllene measured separately. Caryophyllene oxide may form through oxidation and appears separately on some panels.

What does Caryophyllene Oxide smell like?

Common descriptors include dry wood, spice, herbal. Aroma is subjective, and other volatile compounds in the tested product also matter.

What does the research say about Caryophyllene Oxide?

The compound is included in regulated testing and analytical methods. Beta-caryophyllene evidence cannot automatically be assigned to its oxide, and consumer benefits are unestablished.

Does a Caryophyllene Oxide result predict effects?

No. A lab result identifies chemistry in one sample. It does not guarantee a feeling, benefit, dose, or response for an individual consumer.

Keep exploring the chemistry

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