Cannabis use linked to delayed psychiatric care in vulnerable populations

Clusters of social and substance use-related risks are associated with the duration of untreated psychosis.

Psychological medicine • • Moderately Relevant
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AI Summary

This study examines why some patients with psychotic disorders experience long delays before receiving psychiatric care—a critical issue since early intervention significantly improves outcomes. Researchers analyzed data from two large international cohorts totaling 1,627 patients to identify whether specific groups face particular barriers to timely treatment. Using advanced statistical methods, they discovered three distinct subpopulations with different social and substance use characteristics, suggesting that barriers to care are not uniformly distributed across all groups.

The most important finding involves cannabis use as part of a risk cluster: patients who were predominantly younger men with cannabis use and unstable housing experienced 28% longer delays in receiving treatment compared to those with higher education and stable employment (in the GROUP study) and 27% longer delays in the EU-GEI cohort. This association persisted even after accounting for other factors, indicating that cannabis use co-occurs with multiple social disadvantages that collectively delay psychiatric care. Notably, a third group—predominantly women without cannabis use—showed the shortest delays to treatment, suggesting gender and cannabis use patterns intersect in meaningful ways with treatment-seeking behavior.

These findings highlight a crucial public health challenge: vulnerable populations experiencing cannabis use alongside social instability face compounded barriers to mental health care. The research suggests that generic mental health programs may be ineffective for diverse populations and that more targeted, culturally-informed interventions are essential. Understanding these interconnected risk factors—rather than viewing cannabis use in isolation—is critical for developing equitable healthcare systems that reach populations facing the greatest obstacles to timely psychiatric treatment.

📄 Original Abstract

The duration of untreated psychosis (DUP) is still considerably long in patients with psychotic disorders worldwide. Social determinants, such as the socioeconomic status, can influence DUP, exacerbating health inequalities in access to timely care. We investigated whether subpopulations with shared characteristics are associated with longer DUP. We performed latent class analyses to investigate whether classes with shared configurations of social and substance use-related risks can be identified in two large cohorts with psychotic disorders: N = 780 patients from the GROUP project and N = 847 patients from the EU-GEI project. Subsequently, we conducted survival analyses to analyze whether identified classes are associated with DUP. We identified three classes in both samples. Membership of the class with predominantly younger men, higher proportion of cannabis use, and supported living was associated with longer DUP compared with a class with predominantly White ethnicity, higher education, and current employment in GROUP (HR = 1.28, 95% CI: 1.06-1.56, p = .011) and in EU-GEI (HR = 1.27, 95% CI: 1.07-1.51, p = .007). In GROUP, membership of a third class with predominantly White women, without cannabis use, was associated with the shortest DUP (HR = 0.78, 95% CI: 0.63-0.95, p = .016). Results suggest that specific populations differ in their risk distributions for prolonged DUP and highlight the importance of considering configurations of social determinants in context. Public mental health programs need to establish their differential impact for diverse populations and facilitate more targeted pathways to care.

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