Cannabis use disorder linked to 57% higher suicide risk, a concern that won't go away

Cannabis Use Disorder and Suicidal Ideation in the United States: Persistent Risk and Stable Trends, 2014-2023.

Journal of studies on alcohol and drugs • • Moderately Relevant
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AI Summary

This large-scale study examined the relationship between cannabis use disorder (CUD) and suicidal ideation among U.S. adults over a 10-year period (2014-2023), analyzing data from over 415,000 survey respondents. The researchers found that adults with CUD had approximately 57% higher odds of experiencing past-year suicidal ideation compared to those without the condition, after accounting for other demographic and health factors. This elevated risk remained consistent throughout the entire decade studied.

Notably, despite significant changes in the cannabis landscape—including widespread legalization, increased product potency, and shifting public attitudes toward cannabis—the strength of the association between CUD and suicidal ideation did not change over time. The association remained stable across all demographic groups examined, including differences by sex, age, and race/ethnicity. The researchers expected the relationship might weaken as cannabis became more normalized and accepted socially, but their findings suggest this did not occur.

These findings have important implications for mental health and substance use policy. The persistent link between cannabis use disorder and suicide risk indicates that mental health screening and support should remain a priority for individuals struggling with problematic cannabis use, regardless of the changing legal or social context around cannabis. The results suggest that liberalization policies and changing perceptions of cannabis harm have not altered the fundamental psychiatric risks associated with cannabis use disorder, underscoring the need for continued clinical attention and intervention.

📄 Original Abstract

Amid rising cannabis use, declining perceived harm, and policy liberalization over the past 15 years, we examined whether the association between cannabis use disorder (CUD) and past-year suicidal ideation among U.S. adults changed from 2014-2023 and varied by sex, age, and race/ethnicity. Using data from 415,861 adults in the 2014-2023 National Surveys on Drug Use and Health, we examined temporal association change between past-year suicidal ideation and CUD (≥2 of 9 harmonized DSM-5 criteria). Logistic regression models, adjusted for demographic, social, clinical, and geographic covariates, tested whether survey year moderated the CUD-suicidal ideation association overall and in strata by sex, age, and race/ethnicity. Adults with cannabis use disorder had 57% higher odds of past-year suicidal ideation than those without (OR, 1.57; 95% CI, 1.44-1.72) across years. Joint Wald tests showed no evidence that the association changed over time overall (p = 0.12) nor within strata defined by sex or age. Although the joint interaction test suggested some variation among Hispanic respondents (p = 0.01), no individual year-specific interaction terms remained statistically significant after Bonferroni correction. Adults with CUD had higher odds of suicidal ideation but, contrary to expectations, the strength of this association remained stable from 2014-2023 and did not differ significantly across sex, age, or racial/ethnic groups despite widespread legalization, increased potency, and shifting norms.

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