Urine testing reveals widespread substance use among commercial drivers in Ghana

Urine Prevalence of Psychoactive Substances, Nicotine Exposure and Associated Factors Among Commercial Drivers. An Exploratory Study.

Journal of psychoactive drugs • • Moderately Relevant
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AI Summary

This exploratory study examined psychoactive substance use and nicotine exposure among 70 commercial drivers in Ghana using objective urine drug testing rather than relying on self-reported data. The researchers used a 10-panel chromatographic immunoassay test to detect various substances, including THC (the primary psychoactive compound in cannabis). The findings revealed that 61.4% of drivers tested positive for at least one psychoactive substance or nicotine, with nicotine exposure (cotinine) being the most prevalent at 37.1%, followed by 24.3% testing positive for THC, and 11.4% for benzodiazepines. Notably, when drivers were asked about smoking habits, only 10% self-reported smoking, highlighting a significant gap between what people admit to and what objective testing reveals.

The study uncovered an interesting and somewhat counterintuitive finding: commercial drivers who tested positive for certain substances, including tramadol or multiple substances simultaneously, were actually more likely to have no history of road traffic accidents—contrary to what researchers initially expected. This suggests that the simple presence of detectable substances in urine may not directly correlate with dangerous driving behavior or accident risk. The researchers found that 14 drivers (20%) tested positive for two substances, indicating polysubstance use among this population.

These results highlight the importance of using objective biomarkers rather than self-reported questionnaires in substance use research, as evidenced by the stark difference between reported and detected nicotine use. While the study provides valuable data on prevalence rates of various substances among commercial drivers in Ghana, the authors note that further research is needed to better understand the relationship between substance detection and actual driving safety outcomes. The findings challenge assumptions about the automatic link between substance use and traffic accidents, suggesting that additional factors may play important roles in driving safety.

📄 Original Abstract

Earlier studies have documented psychoactive substance use and nicotine exposure among commercial drivers in Ghana. However, those studies relied solely on self-reported questionnaires, which are prone to recall and response bias. This study aimed to provide a more accurate estimate by using a chromatographic immunoassay urine drug test. This exploratory cross-sectional study was conducted between January and August 2024 in the Tamale metropolitan area of Ghana. The study included 70 consenting commercial drivers aged from 26 to 78 years. Sociodemographic, anthropometric and occupational factors were collected using a semi-structured questionnaire. Urine samples were then obtained from the participants and tested for Amphetamine (AMP), Barbiturates (BAR), Benzodiazepines (BZO), Cocaine (COC), Tetrahydrocannabinol (THC), Morphine (MOP), Opiates (OPI), nicotine exposure using Cotinine (COT), Tramadol (TML), and Tricyclic Antidepressants (TCA) using the 10-panel Multi-Drug One Step chromatographic immunoassay test kit. The total urine prevalence of psychoactive substances and nicotine exposure was 61.4%, consisting of COT (37.1%), THC (24.3%), BZO (11.4%), Tramadol (5.7%) and AMP (2.9%). While the self-reported smoking prevalence was 10%, the urine cotinine prevalence was 37.1%. In addition, 14(20%) of the urine samples tested positive for two substances. Contrary to expectations, commercial drivers with no history of accident were more likely to test positive for TML [AOR = 8.667(95%CI: 1.025-73.249)], or two substances [AOR = 5.000(95%CI: 1.051-23.789)]. The urine samples of commercial drivers tested positive for psychoactive substances and nicotine exposure. However, positivity for a psychoactive substance or nicotine exposure may not be associated with a history of road traffic accidents. Further studies are recommended.

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