Pregnant users turn to cannabis for mood relief, real-time study shows

Use of cannabis to regulate negative affect in pregnancy: Bidirectional findings from an ecological momentary assessment study.

Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors • • Moderately Relevant
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AI Summary

This groundbreaking ecological momentary assessment study provides the first real-time evidence that pregnant individuals use cannabis to manage negative emotions like anxiety, depression, and irritability. Researchers followed 20 pregnant participants (average 22.5 weeks gestation) over a 14-day period, collecting data on mood and cannabis use across an average of nearly 15 use events per person. The findings reveal a clear bidirectional relationship: higher levels of momentary negative affect predicted increased likelihood of cannabis use, suggesting that emotional regulation drives prenatal cannabis consumption.

The research also demonstrates that cannabis use itself produces short-term relief from depression, anxiety, and irritability, creating a potential reinforcement cycle. After consuming cannabis, participants reported measurable reductions in all three forms of negative affect, supporting what researchers call the affect regulation hypothesis—the idea that people use cannabis specifically to manage difficult emotions. This short-term mood improvement may encourage repeated use, establishing a pattern where relief from emotional distress becomes the primary driver of continued prenatal cannabis consumption.

These findings carry significant clinical implications, as they identify a key mechanism maintaining prenatal cannabis use during a critical period of fetal development. Understanding that mood regulation motivates cannabis use in pregnancy opens pathways for targeted mental health interventions. Rather than simply discouraging use, healthcare providers may need to address underlying anxiety and depression through evidence-based treatments, offering pregnant individuals healthier alternatives for managing negative emotions. The study highlights the urgent need for comprehensive prenatal mental health screening and support to reduce cannabis use during pregnancy."

📄 Original Abstract

Prenatal cannabis use is increasing in the United States, despite evidence of potential harms to pregnant individuals and their offspring. Elevated rates of anxiety and depression among those who use cannabis during pregnancy suggest that mental health difficulties may contribute to prenatal cannabis use. In line with the affect regulation hypothesis, many pregnant individuals endorse using cannabis to manage mood. However, no studies have examined this relationship in real time. Moreover, the acute effects of cannabis on mood during pregnancy remain understudied, limiting knowledge of whether negative affect (NA) relief reinforces continued use. Addressing these gaps, the present study examines the relationship between momentary NA and cannabis use in pregnant adults and explores the effect of cannabis on NA. Participants (N = 20, Mage = 30.15, Mgestationalage = 22.5 weeks, 60% White) completed a baseline session followed by a 14-day ecological momentary assessment burst (average of 14.95 cannabis use events per burst). Generalized linear mixed-effects models tested whether momentary ratings of depression, anxiety, and irritability predicted subsequent cannabis use (Aim 1), and linear mixed-effects models tested whether cannabis use predicted subsequent changes in NA (Aim 2). Aim 1 results indicated that greater levels of NA (momentary depression, anxiety, and irritability) were associated with greater odds of using cannabis. Aim 2 results suggest cannabis use was followed by reductions in depression, anxiety, and irritability, reflecting short-term NA relief. Findings provide the first real-time evidence supporting the affect regulation hypothesis in pregnancy and highlight the potential reinforcing role of NA relief in sustaining prenatal cannabis use. (PsycInfo Database Record (c) 2026 APA, all rights reserved).

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