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Limonene

LIM-oh-neen /ˈlɪməniːn/

Second most abundant terpene. Limonene provides uplifting effects and may help with anxiety and depression without psychotropic side effects.

Concentration
0.1-0.3% (can exceed 0.5%)
Strains Found
50+

Aroma Profile

Citrus, lemon, orange

Flavor Notes

Sweet citrus, tangy

Also Found In

Citrus fruits Rosemary Peppermint Juniper

Primary Effects

Anxiety reduction
Mood elevation
Stress relief
GABA enhancement

How It Works

  • Modulates adenosine A2A receptors
  • Reduces pro-inflammatory cytokines (TNF-α, IL-1β)
  • Enhances GABA activity
  • Does not strongly bind CB receptors

Clinical Evidence

2024 cross-over study: Vaporizing 1-5mg limonene with THC significantly reduced THC-induced anxiety without diminishing therapeutic effects. Limonene acts via adenosine A2A receptors and reduces pro-inflammatory cytokines.

Strains with Limonene

Explore 50 cannabis strains where Limonene is the dominant terpene

Limonene FAQs

What is Limonene?

Second most abundant terpene. Limonene provides uplifting effects and may help with anxiety and depression without psychotropic side effects.

What are the effects of Limonene?

Limonene is known for Anxiety reduction, Mood elevation, Stress relief, GABA enhancement effects.

What does Limonene smell like?

Limonene has a citrus, lemon, orange aroma and sweet citrus, tangy flavor.

How many Limonene-dominant strains are there?

We have 50 strains where Limonene is the dominant terpene in our database.

Want to learn more about cannabis terpenes?

Explore all 17 terpenes and discover which strains match your preferences

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