22
22 is a perfectly balanced hybrid (50/50) from Cali Connection, crossing legendary Jack Herer with OG Kush. Testing 17.8-29% THC, this strain delivers simultaneous mental clarity and physical relaxation through a terpene profile dominated by limonene, caryophyllene, and myrcene. Expect pine, citrus, and spicy aromatics with creative euphoria that keeps you focused and motivated while soothing muscle tension. True "anytime" versatilityโfunctional enough for daytime productivity, relaxing enough for evening unwinding.
Quick Hits
These are approximate averages from community data. Your actual product's THC/CBD varies by batch, grower, and growing conditions.
Scan your label for exact values โClassification based on genetic lineage. Note: Recent research shows indica/sativa labels don't predict effectsโterpene profiles do.
The dominant aromatic compound shaping this strain's effects and flavor profile. Terpenes work with cannabinoids to create your unique experience.
Recommendation based on typical effects. Morning strains tend to energize; evening strains tend to relax. Your experience may vary.
When this strain was first cultivated or its genetic origin decade. Heritage strains often have more stable, established genetics.
Market availability based on dispensary listings and community data. Rare strains may require searching specialty dispensaries.
Strain Highlights
Key insights at a glance
Professor High Says...
In-depth strain breakdown from our cannabis expert
The first wave hits behind the eyesโthis bright, crystalline mental clarity that feels like someone just cleaned my cognitive windows. The limonene lifts my mood immediately, bringing this genuine smile-inducing euphoria that's never forced or manic. What's remarkable here is how the cerebral energy doesn't create anxiety; instead, the caryophyllene and myrcene provide this underlying cushion of calm that lets creative thoughts flow freely.
My body feels like it's finally exhaling after holding tension I didn't realize I was carrying. Shoulders drop, jaw unclenches, but I'm absolutely not stuck anywhere. I actually want to move, create, engageโthere's this productive motivation paired with physical ease. It's like my mind says "let's write something brilliant" while my body says "yes, and let's feel comfortable doing it." The balance is the magicโneither mind nor body dominates. This is functional cannabis at its finest, where enhancement doesn't mean impairment, and relaxation doesn't mean sedation. This is why hybrid breeding matters.
Effects Profile
Best enjoyed during anytime
Balanced for any time of day
Best For
Effect Sources
- 122 Weed Strain Informationleafly.com
- 222 OG Marijuana Strain Information & Reviewsallbud.com
- 3Blue #22 (Breeder Cut) 7g Hybrid 26.6% | 2.40% Terpsmontrosecannabis.ca
- 4List of 7,233 Cannabis Strainsstrainsdb.org
- 5The Top 5 Strongest Cannabis Strains โ 2025 Update - RQS Blogroyalqueenseeds.com
- 6Descubre las 5 variedades mรกs populares en EE.UU. - RQS Blogroyalqueenseeds.com
- 7Top 10 Hybrid Strains - RQS Blogroyalqueenseeds.com
7 verified sources
Side Effects
Side Effects Coming Soon
User-reported effects are being collected
Aroma & Flavors
Aroma & Flavor Sources
- 122 Weed Strain Informationleafly.com
- 222 OG Marijuana Strain Information & Reviewsallbud.com
- 3Blue #22 (Breeder Cut) 7g Hybrid 26.6% | 2.40% Terpsmontrosecannabis.ca
- 4List of 7,233 Cannabis Strainsstrainsdb.org
- 5Descubre las 5 variedades mรกs populares en EE.UU. - RQS Blogroyalqueenseeds.com
- 6Top 10 Hybrid Strains - RQS Blogroyalqueenseeds.com
- 7Top 10 New Weed Strains 2024 - RQS Blogroyalqueenseeds.com
- 8Purple Kush: Indica Bliss From the Hindu Kush Mountains - RQS Blogroyalqueenseeds.com
8 verified sources
Aromas
Flavors
Appearance
Appearance Details Coming Soon
Visual characteristics are being documented
Terpene Profile
Partially VerifiedTerpene Sources
- 122 Weed Strain Informationleafly.com
- 222 OG Marijuana Strain Information & Reviewsallbud.com
- 3Blue #22 (Breeder Cut) 7g Hybrid 26.6% | 2.40% Terpsmontrosecannabis.ca
- 4List of 7,233 Cannabis Strainsstrainsdb.org
- 5The Best Cannabis Strains of All Time - RQS Blogroyalqueenseeds.com
- 6Discover the Top New Weed Strains of 2024 - RQS Blogroyalqueenseeds.com
6 verified sources
Terpene Distribution
Limonene
Flavor: Citrus, lemon, orange
Full Profile
Limonene
1.61 %
Flavor Profile:
Citrus, lemon, orange
Effects:
Caryophyllene
1.57 %
Flavor Profile:
Spicy, peppery, woody
Effects:
Myrcene
0 %
Flavor Profile:
Earthy, musky, fruity
Effects:
Pinene
0 %
Flavor Profile:
Pine, fresh forest
Effects:
Linalool
0 %
Flavor Profile:
Floral, lavender, sweet
Effects:
Humulene
0 %
Flavor Profile:
Hoppy, woody, earthy
Effects:
Terpinolene
0 %
Flavor Profile:
Fresh, piney, floral, citrus
Effects:
Cannabinoid Profile
Extended Cannabinoid Profile Coming Soon
Detailed lab data is being collected
Medical Effects
Medical Effect Sources
- 122 Weed Strain Informationleafly.com
- 2Blue #22 (Breeder Cut) 7g Hybrid 26.6% | 2.40% Terpsmontrosecannabis.ca
- 3List of 7,233 Cannabis Strainsstrainsdb.org
- 4Which Cannabis Strain Should I Smoke? - RQS Blogroyalqueenseeds.com
- 5Space Cookies Weed Strain Review & Informationcannabistraininguniversity.com
5 verified sources
Mental Effects
- โขAnxiety relief
Users report reduced anxiety and racing thoughts. The balanced cannabinoid profile provides calming cerebral effects without overwhelming sedation.
- โขStress relief
Commonly used for stress management. The combination of creative and relaxing effects helps users decompress while maintaining mental clarity.
- โขDepression support
Reported to lift mood and provide gentle euphoria. The uplifting effects may help with low mood without inducing paranoia or anxiety.
- โขFocus and mental clarity
Despite relaxing properties, users report maintained focus for creative and analytical tasks. Effects are balanced rather than sedating.
Professor High visualization
Body Effects
- โขPain relief
Mild to moderate analgesic properties reported. Users experience muscle tension relief without complete immobilization.
- โขMuscle relaxation
Helps ease muscle spasms and tension. The myrcene content contributes to body relaxation.
- โขInsomnia support
Some users report improved sleep quality, particularly at higher doses or later in the day. Not strongly sedating for all users.
- โขGeneral relaxation
Provides physical ease and comfort without couch-lock. Users maintain mobility and can engage in activities.
Medical Disclaimer: This information is AI-generated based on available research and user reports, provided for educational purposes only, and is not intended as medical advice. Cannabis affects everyone differently. Consult with a qualified healthcare professional before using cannabis for medical purposes. Do not use cannabis if pregnant, nursing, or have a medical condition without consulting your doctor.
Lineage History
Lineage Sources
- 122 Weed Strain Informationleafly.com
- 222 OG Marijuana Strain Information & Reviewsallbud.com
- 3List of 7,233 Cannabis Strainsstrainsdb.org
- 4The Best Cannabis Strains of All Time - RQS Blogroyalqueenseeds.com
- 5Which Cannabis Strain Should I Smoke? - RQS Blogroyalqueenseeds.com
- 6Taste and Effects of Cannabis Strains: A Guide - Royal Queen Seeds USAroyalqueenseeds.com
- 7Purple Kush: Indica Bliss From the Hindu Kush Mountains - RQS Blogroyalqueenseeds.com
- 8Space Cookies Weed Strain Review & Informationcannabistraininguniversity.com
8 verified sources
22 appears to have multiple lineages depending on phenotype. The most consistent breeding information credits Cali Connection with creating a cross between Jack Herer and OG Kush, resulting in a balanced hybrid that combines the creative, energetic properties of Jack Herer with the relaxing, potent effects of OG Kush.
Genetics
Breeder
Cali Connection
Historical information is actively being researched. Details will be updated as more verified data becomes available.
Consumption Methods
Consumption Methods Coming Soon
Our research team is gathering usage recommendations
Awards & Recognition
Notable Mentions
Strain Reviews & Videos
Detailed Description
An Enigmatic Balanced Hybrid
Strain 22 presents a fascinating case study in modern cannabis breedingโa balanced hybrid that combines the legendary genetics of Jack Herer and OG Kush to create an experience that satisfies both mind and body equally. Bred by Cali Connection during the 2010s, this strain emerged during cannabis culture's golden age of genetic experimentation, when breeders sought to merge the cerebral clarity of sativas with the physical comfort of indicas. Testing between 17.8-29% THC with minimal CBD (0.5-1%), 22 delivers potent effects while maintaining remarkable functional balance.
๐งฌ Genetic Heritage & Lineage
The Jack Herer parentage brings legendary sativa-dominant genetics known for creative energy and mental clarity, while OG Kush contributes its signature relaxing properties and complex terpene profile. This combination creates what cannabis connoisseurs call a "true 50/50 hybrid"โneither indica nor sativa dominates the experience. The Cali Connection's breeding work focused on stabilizing this balance, resulting in a cultivar that inherited Jack Herer's motivational qualities without sacrificing OG Kush's therapeutic relaxation. Worth noting: the "22" designation has been used by multiple breeders for different phenotypes (including Sherbanger #22, Boston Tea Party #22, and others), but the most widely recognized version remains this Jack Herer x OG Kush cross.
๐ Terpene Profile & Aromatics
22's terpene profile creates an aromatic symphony dominated by three key players. Limonene leads at approximately 1.61%, delivering bright citrus notes with mood-elevating properties. Caryophyllene follows closely at 1.57%, contributing spicy pepper undertones while binding to CB2 receptors for anti-inflammatory effects. Myrcene rounds out the profile with earthy, musky notes that enhance the body-calming experience.
When you open a container of 22, you'll immediately notice sharp pine and citrus aromas reminiscent of a forest after rain, followed by spicy, peppery notes and subtle floral undertones. The sage-like herbal quality becomes more apparent as the buds warm in your hands, while deeper earthy and diesel notes emerge. Some phenotypes express sweet berry characteristics alongside the dominant pine-citrus-spice trinity.
๐ Flavor Experience
The flavor journey mirrors the aromatic complexity. Your first inhale brings crisp pine and zesty citrus that coat the palate, transitioning mid-session to earthy diesel with herbal sage notes. The spicy pepper from caryophyllene creates pleasant tingle on the tongue, while subtle berry sweetness emerges on the exhale. The aftertaste lingers with pine resin and sage, leaving your mouth feeling refreshed rather than overwhelmed. Some users detect cheese-like undertonesโa signature characteristic inherited from certain OG Kush phenotypes.
๐ฏ Effects & Experience
The effects profile truly showcases 22's balanced hybrid nature. Onset begins within 5-10 minutes, starting with cerebral euphoria that lifts your mood and sparks creative thinking. You'll notice enhanced focus and mental clarity without the racing thoughts that pure sativas sometimes trigger. This mental stimulation feels productive and motivatingโperfect for tackling projects or engaging conversations.
Simultaneously, gentle physical relaxation begins in your shoulders and neck, gradually spreading throughout your body. This isn't sedating couch-lock; rather, it's soothing muscle ease that releases tension while maintaining mobility. The peak arrives 30-45 minutes post-consumption, where mental uplift and physical comfort reach equilibrium. You'll feel energetic yet calm, creative yet grounded, happy yet focused.
Effects typically last 2-3 hours, tapering gradually without harsh comedown. Higher doses may induce more pronounced relaxation and occasional sleepiness, making dosage control important for desired outcomes.
๐ฎ Use Cases & Activities
22's balanced profile makes it genuinely anytime appropriate. Morning sessions support creative work and focused tasks without morning grogginess. Afternoon use enhances social gatherings and outdoor activitiesโthe strain's mood-elevating properties encourage conversation while maintaining mental sharpness. Early evening consumption pairs beautifully with meditation or light exercise like yoga or hiking, where you'll appreciate the mind-body connection.
๐ Medical & Therapeutic Potential
Users report 22 may help with both mental and physical concerns. The anxiety-reducing effects (rated 4/5 intensity) come from the combined action of limonene's mood elevation and myrcene's calming properties. Stress relief similarly benefits from this terpene synergy. For depression support, the uplifting euphoria provides gentle mood enhancement without overwhelming stimulation.
Physically, the strain may offer mild-to-moderate pain relief and muscle relaxation (both rated 3/5 intensity) through caryophyllene's CB2 receptor activation. Some users find it helps with insomnia, though effects varyโhigher doses tend to promote sleep more effectively. The strain's focus-enhancing properties may benefit those managing attention difficulties.
๐๏ธ Visual Characteristics
Buds typically display medium-to-dense structure with forest green coloring accented by purple undertones in cooler-grown phenotypes. Bright orange pistils weave throughout, while a generous coating of frosty trichomes signals potency. The buds often show the classic OG Kush bud structureโchunky, resinous, and visually appealing.
๐ Awards & Recognition
While 22 itself hasn't garnered major competition wins, related genetics like Sweet ZZ (a similar genetic profile) won the 2011 High Times Medical Cup in the concentrate category, demonstrating the therapeutic potential of these terpene profiles.
โ ๏ธ Consumer Considerations
Best for: intermediate-to-experienced consumers who appreciate balanced effects; newcomers should start with lower doses due to THC potency. The strain's versatility makes it ideal for those seeking daytime functionality with relaxation or creative focus with stress relief. Potential side effects include typical dry mouth and dry eyesโstay hydrated. The balanced nature means fewer reports of anxiety or paranoia compared to pure sativas, though individual responses vary.
With its legitimate all-day versatility, 22 represents thoughtful breeding at its finestโa strain that refuses to be pigeonholed, offering something valuable for nearly every cannabis consumer's needs.
Research Methodology
How we compiled this strain profile
This strain profile was generated by analyzing 34 independent sources mentioning '22'. Our research pipeline cross-references multiple databases, lab results, and community reports to synthesize accurate strain data.
Data Quality by Section
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Strain Highlights
Key insights at a glance
Lineage History
Lineage Sources
- 122 Weed Strain Informationleafly.com
- 222 OG Marijuana Strain Information & Reviewsallbud.com
- 3List of 7,233 Cannabis Strainsstrainsdb.org
- 4The Best Cannabis Strains of All Time - RQS Blogroyalqueenseeds.com
- 5Which Cannabis Strain Should I Smoke? - RQS Blogroyalqueenseeds.com
- 6Taste and Effects of Cannabis Strains: A Guide - Royal Queen Seeds USAroyalqueenseeds.com
- 7Purple Kush: Indica Bliss From the Hindu Kush Mountains - RQS Blogroyalqueenseeds.com
- 8Space Cookies Weed Strain Review & Informationcannabistraininguniversity.com
8 verified sources
22 appears to have multiple lineages depending on phenotype. The most consistent breeding information credits Cali Connection with creating a cross between Jack Herer and OG Kush, resulting in a balanced hybrid that combines the creative, energetic properties of Jack Herer with the relaxing, potent effects of OG Kush.
Genetics
Breeder
Cali Connection
Historical information is actively being researched. Details will be updated as more verified data becomes available.
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