Knock Out

Knock Out is a potent hybrid strain (50-70% indica) with THC levels ranging from 18-34%, delivering powerful euphoric and sedating effects. Its myrcene-dominant terpene profile creates earthy, sweet, and gassy aromas with pine and citrus notes. Perfect for evening use, this strain excels at pain relief, stress reduction, and promoting deep sleep, though its knockout sedation makes it unsuitable for daytime activities.

The Short Answer

What kind of high is Knock Out?

Myrcene-led and sweet-citrus on the palate, most often reported relaxed and picked for evening wind down at night.

Terpenes decide how a strain feels — THC% only decides how strong the dose is. Here is the family, the chemistry behind it, and what people reach for it to do.

High Family
Relaxing High
Deep Body Relaxation
🔥 THC-Dominant
Dominant Terpenes
myrcene
Smells Earthy, musky, fruity
  • Sedating
  • Muscle relaxant
  • Anti inflammatory
  • caryophyllene Spicy, peppery, woody
  • limonene Citrus, lemon, orange

Ordered by measured share — the exact percentages shift with every batch and cure.

How It Feels
Relaxed
  • Euphoric
Best For
Tastes Like
Sweet citrus
  • Earthy
Smells Like
Pungent citrus
  • Sweet
  • Earthy
  • Best Time night
  • Era
  • Rarity

Genetics Hybrid A lineage label, not an effects predictor — most modern flower is a hybrid, and the terpene mix above is what you will actually notice.

Potency Check the label, not the strain Varies by batch, grower and harvest — check the label on the product you are buying. Scan your label → Reported ranges →

Heads up Most reported: dry mouth and dry eyes. Responses vary — start low, go slow. Review safety →

This strain has its own song — hit play, read along, and chill out.

Knock Out Soundtrack

AI-generated for this strain

Metal80 BPMAb major
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Strain Highlights

Key insights at a glance

1
Powerhouse hybrid with 18-34% THC delivering euphoric relaxation and deep sedation
2
Myrcene-dominant terpene profile creates earthy, sweet aromas with diesel and citrus notes
3
Exceptional for pain relief, muscle tension, and insomnia with profound body effects
4
Heavy couch-lock potential makes this strictly an evening or nighttime strain

The Experience

Professor High Avatar

Professor High Says...

In-depth strain breakdown from Professor High, our AI cannabis expert

4.2 / 5 Rated 4.2 out of 5 by Professor High

The moment I exhaled that first hit of Knock Out, I felt this warm wave of euphoria washing over my consciousness—like my brain just got wrapped in a cozy blanket made of endocannabinoids. The mental uplift hits fast, bringing this pleasant giggly contentment where everything seems just a bit more amusing and interesting. But here's where the science gets fascinating: as those myrcene molecules bind to CB1 receptors throughout my body, I'm experiencing this progressive muscle relaxation that starts in my shoulders and cascades downward like a slow-motion waterfall of relief.

The caryophyllene is clearly doing its job as a CB2 agonist, because that chronic lower back tension I carry is just... melting away. By minute twenty, I'm in what I call the "deep couch integration phase"—my body has achieved such profound relaxation that moving seems entirely optional. The limonene keeps things from getting too heavy, maintaining this underlying brightness to the experience that prevents complete sedation for the first hour or so. This is textbook biphasic cannabis response: initial stimulation followed by deep sedation, perfectly orchestrated by this strain's terpene symphony.

Hybrid
Myrcene Forward
night Use

Effects Profile

Relaxed · Euphoric
Relaxed Euphoric

Best enjoyed during night

Deep relaxation and sleep

Best For

Evening Wind Down · Sleep & Bedtime · Relaxing

Look, Aroma & Taste

Aroma & Flavor

Sweet · Earthy · Citrus

Aromas

Sweet
Earthy
Citrus
Pine
Pungent

Flavors

Sweet
Earthy
Citrus

Terpene Profile

Myrcene leads · 3 terpenes mapped
Total Terpene Content: 0.94% (Low)

Terpene Distribution

Terpene profile: Myrcene 0.5%, Caryophyllene 0.3%, Limonene 0.2% .

Myrcene

Flavor: Earthy, musky, fruity

Sedating Muscle relaxant Anti-inflammatory

Caryophyllene

Flavor: Spicy, peppery, woody

Anti-inflammatory Pain relief Anti-anxiety

Limonene

Flavor: Citrus, lemon, orange

Anxiety reduction Mood elevation Stress relief

Appearance

Deep forest green · Purple undertones

Color Palette

deep forest green
purple undertones
dark emerald
vibrant orange pistils
amber trichomes
rust-colored hairs

Texture

Dense, tightly-packed bud structure with heavy resin coverage and sticky texture typical of indica-dominant genetics

Crystal Density

very high

Exceptional crystal coverage

Chemistry & Research

Medical Effects

9 reported therapeutic uses on file

Mental Effects

45 %
  • Anxiety Relief

    Reduces anxiety and promotes calm without heavy sedation

  • Stress Relief

    Alleviates stress and tension for mental relaxation

  • Depression Support

    Helps elevate mood and combat depressive symptoms

  • Focus Enhancement

    Improves mental clarity and concentration abilities

Professor High visualization

Body Effects

55 %
  • Pain Management

    Reduces chronic pain and general discomfort effectively

  • Muscle Relaxation

    Eases muscle tension and spasm relief significantly

  • Inflammation Reduction

    Decreases inflammatory conditions throughout the body

  • Sleep Support

    Promotes restful sleep and addresses insomnia symptoms

  • Appetite Stimulation

    Increases appetite and helps with eating difficulties

Medical Disclaimer: This information is AI-generated based on available research and user reports, provided for educational purposes only, and is not intended as medical advice. Cannabis affects everyone differently. Consult with a qualified healthcare professional before using cannabis for medical purposes. Do not use cannabis if pregnant, nursing, or have a medical condition without consulting your doctor.

What Research Says

Peer-reviewed studies, terpene science & safety guidance

What does the research say about Knock Out?

Knock Out is a hybrid cannabis strain containing up to 34.8% THC, with a terpene profile dominated by Myrcene and Caryophyllene. This page currently has good data confidence. Below are profile sources when available plus authoritative resources for understanding the compounds in this strain.

Educational resources only — not medical advice. Always consult a qualified clinician for health decisions.

Cannabinoids (THC & CBD)

THC 10-34.81% · Type I chemovar

THC% tells you how strong. Terpenes tell you how it feels.

THC percentage is a property of the product in your hand, not of the strain. It shifts with the batch, the grower, the harvest, and how the flower was cured and stored — the same strain can test several points apart from two different jars.

Treat the ranges below as market context for what to expect on a shelf — then read the actual label on the product you are buying, and use the terpene profile to judge how it will feel.

Type I THC-Dominant

High THC (>15%), low CBD (<1%) - Most common recreational strains

Reported THC Range
10-34.81%

Using It Well

Consumption Methods

Smoking · Vaping · Edibles

Recommended Methods

Smoking
Vaping
Edibles
Tinctures

Side Effects

Dry Mouth · Dry Eyes · +3 more

Side effects vary by individual. Start low, go slow. Consult a healthcare professional with concerns.

Dry Mouth
Dry Eyes
Drowsiness
Couch-Lock
Dizziness

These are commonly reported effects. Individual experiences may vary based on dosage, tolerance, and consumption method.

Where It Comes From

Lineage & History

Triangle Kush × OG Kush

Knock Out is a hybrid strain with multiple genetic lineages reported across sources. Primary lineages include Triangle Kush × OG Kush, The White × Chem 4 OG, and Khalifa Kush × The Menthol. Some sources indicate XXX × End Game #3 parentage, while others report Blue Dream × Granddaddy Purple crosses. The strain has been bred by multiple genetics companies including Knock Out Genetics, Crop King Seeds, Happy Valley Genetics, and others.

Historical information is actively being researched. Details will be updated as more verified data becomes available.

Awards & Recognition

1 award & mention

The Full Story

Detailed Description

The long-form profile · ~4 min read

Introduction to Knock Out Cannabis Strain

Knock Out lives up to its name as a powerhouse hybrid that delivers a profound relaxation experience wrapped in a complex flavor profile. This strain has become a staple for evening wind-down sessions, earning its reputation through potent THC levels ranging from 18-34% and a terpene-rich composition that creates a memorable sensory journey. Whether you're seeking relief from chronic pain or simply looking to melt into your couch after a long day, Knock Out offers a euphoric yet deeply calming experience that has captivated cannabis enthusiasts across multiple markets.

🧬 Genetic Heritage & Lineage

The genetic story of Knock Out is refreshingly diverse, with multiple breeding lines contributing to various phenotypes under the same name. The most prominent lineage traces back to Triangle Kush × OG Kush, creating that classic OG foundation known for its sedating properties and earthy gas profile. Other notable versions include crosses with The White × Chem 4 OG from Crop King Seeds, Khalifa Kush × The Menthol popularized through Tyson 2.0 branding, and even Blue Dream × Granddaddy Purple from Pure Sunfarms. This genetic diversity means you'll find variations in effect profiles and flavor notes depending on the breeder, but all share that signature knockout punch of relaxation and euphoria.

👃 Terpene Profile & Aromatics

Knock Out's aromatic complexity comes from its dominant myrcene content (averaging 0.45%), which provides that earthy, musky foundation characteristic of indica-leaning hybrids. Caryophyllene follows at 0.31%, adding spicy, peppery notes and contributing to the strain's anti-inflammatory properties. Limonene rounds out the top three at 0.18%, introducing bright citrus highlights that cut through the earthiness. When you open a jar of Knock Out, you'll encounter an initial wave of sweet, pungent earthiness mingled with pine and diesel fuel, followed by subtle fruity undertones and a gassy, chemical edge that signals its OG lineage. The aroma intensifies when grinding, releasing those terpenes and filling the room with a complex bouquet that's simultaneously sweet, sharp, and deeply herbaceous.

👅 Flavor Experience

The flavor journey of Knock Out mirrors its aromatic profile but with added depth on the palate. On the inhale, you'll taste sweet earthiness mixed with woody pine notes and a hint of citrus zest. The mid-palate reveals spicy, peppery undertones from the caryophyllene, along with subtle fruity sweetness reminiscent of berries or candy. The exhale leaves a lingering diesel-gas flavor with herbal and earthy finish that coats your mouth pleasantly. Some phenotypes express more candy-like sweetness, while others lean heavier into the fuel and chemical notes. The smoke or vapor is typically smooth despite the potency, making for an enjoyable consumption experience.

🎯 Effects & Experience

Knock Out delivers a two-phase experience that begins with mental uplift before settling into deep physical relaxation. Within 5-10 minutes of consumption, you'll notice a euphoric head rush that elevates mood and brings on feelings of happiness and contentment. This initial cerebral stimulation often sparks creativity and focus, making it suitable for light activities before the indica side takes hold. After 15-20 minutes, the body effects intensify, bringing profound muscle relaxation and a heavy, sedating sensation that many describe as being knocked out (hence the name). The peak effects last 2-3 hours, during which you may experience sleepiness, couch-lock, and increased appetite. This strain is particularly effective for evening and nighttime use, as the sedation can be quite pronounced, especially at higher doses.

💚 Medical & Therapeutic Potential

Knock Out's myrcene-dominant profile combined with substantial caryophyllene content makes it particularly valuable for pain management and inflammation reduction. Medical users report significant relief from chronic pain conditions, muscle spasms, and tension headaches. The strain's anxiolytic properties may help with anxiety and stress, though the high THC content means starting with small doses is advisable for anxiety-prone individuals. The sedating effects make Knock Out especially useful for insomnia and sleep disorders, helping users achieve deeper, more restful sleep. Some consumers also find it helpful for appetite stimulation and mood enhancement, potentially offering support for depression symptoms.

👁️ Visual Characteristics

Knock Out buds present with dense, tightly-packed structure typical of indica genetics. The primary coloration features deep forest green with purple undertones becoming more prominent in cooler growing conditions. Vibrant orange to rust-colored pistils twist throughout the flowers, creating striking contrast against the green backdrop. The most notable visual feature is the heavy trichome coverage - these buds are often frosted with crystalline resin, giving them a sticky, sparkly appearance under light. The medium to high crystal density indicates the strain's potent cannabinoid content and explains why handling these buds leaves your fingers coated in resin.

⚠️ Consumer Considerations

With THC levels regularly exceeding 24% and sometimes reaching above 30%, Knock Out is best suited for experienced consumers or those with established tolerance. Novice users should start with very small amounts and wait to assess effects before consuming more. Common side effects include dry mouth and dry eyes, so keep water and eye drops handy. The sedating properties make this strain inappropriate for daytime use unless you have no responsibilities requiring alertness. The couch-lock potential is real, so plan your consumption accordingly and ensure you're in a comfortable environment where you can fully relax into the experience.

Research Methodology

How we compiled this strain profile

64%
Data Confidence

This strain profile was compiled from 24 published sources covering 'Knock Out'. Our research pipeline cross-references these sources and reports how strongly they agree — see the confidence breakdown below.

Data Quality by Section

Terpenes Low (11 sources)
Effects Low (14 sources)
Lineage Low (12 sources)
Medical Low (8 sources)
Aromas Low (13 sources)
Cannabinoids Low (10 sources)
Last updated: August 8, 2026

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