Guptilla
aka GG4, Gtl
Guptilla is a potent 70/30 indica-dominant hybrid born from Gorilla Glue #4 and Gupta Kush, crafted by Colorado Seed Inc. With THC reaching up to 29%, it delivers a euphoric cerebral lift followed by deep, sedating body relaxation. Its complex terpene profile blends citrus, diesel, floral, and earthy notes into a rich sensory experience perfect for evening wind-down and stress relief.
The Short Answer
What kind of high is Guptilla?
Limonene-led and earthy-grape on the palate, most often reported euphoric and picked for sleep & bedtime at night.
Terpenes decide how a strain feels — THC% only decides how strong the dose is. Here is the family, the chemistry behind it, and what people reach for it to do.
Terpenes are the aromatic compounds that shape the character of a high. The blend a strain carries — not its THC percentage — is what makes one feel bright and social and another heavy and sleepy, which is why the top three are listed rather than just the leader.
Terpene percentages belong to the jar, not the strain. They move with harvest timing, drying, cure and shelf age — the lighter ones literally evaporate. What holds steady is which terpenes lead, so that is what we rank.
See the full profile →Learn how terpenes work →- Anxiety reduction
- Mood elevation
- Stress relief
- Caryophyllene Spicy, peppery, woody
- Myrcene Earthy, musky, fruity
Ordered by measured share — the exact percentages shift with every batch and cure.
The effects reported most often across our research sources. Every body is different — set, setting and tolerance all move the result.
- Relaxed
- Happy
The activities this strain gets picked for most often, leading with the specific ones rather than the broad buckets nearly every strain shares. A starting point, not a prescription — what works for you is personal.
See the full list →The flavor notes reported most often across our research sources, led by the most specific one — flavor tracks the terpene blend, but cure, age and how you consume it all shift what actually lands on the palate.
See the full profile →- Citrus
The aroma notes reported most often across our research sources — what the jar gives up before you light it. This is the strain's own recorded profile, not the textbook aroma of its lead terpene.
See the full profile →- Earthy
- Best Time night
- Era 2019
- Rarity Common
Genetics Indica-Dominant Hybrid A lineage label, not an effects predictor — most modern flower is a hybrid, and the terpene mix above is what you will actually notice.
Potency Check the label, not the strain Varies by batch, grower and harvest — check the label on the product you are buying. Scan your label → Reported ranges →
Heads up Most reported: dry mouth and dry eyes. Responses vary — start low, go slow. Review safety →
Your guided read
6 chapters on Guptilla
Start at the top and work down — each chapter builds on the one before it. Jump to any chapter to read it on its own.
- The Experience How this strain is reported to feel, and when people reach for it.
- Look, Aroma & Taste The smell and flavour you will actually notice — and the terpenes behind them.
- Chemistry & Research Therapeutic reports, published research, and what the lab numbers do — and do not — tell you.
- Using It Well Consumption methods that suit this strain, and the side effects to plan around.
- Where It Comes From The genetics, the breeders, and the recognition it has picked up along the way.
- The Full Story The long-form profile and community video reviews, once you want the detail.
Strain Highlights
Key insights at a glance
The Experience
Professor High Says...
In-depth strain breakdown from Professor High, our AI cannabis expert
Okay, so the first thing that hits me — even before the exhale — is this bright citrusy lift that floods the frontal lobe. It's like the limonene just flips a switch and suddenly everything feels lighter, warmer, more interesting. My thoughts are moving with a kind of clear, energized quality — not racing, just engaged. Then, maybe ten minutes in, the GG#4 lineage makes itself known. There's this gradual, almost tectonic shift from mental to physical — like warm water slowly filling every muscle cavity. My shoulders drop. My jaw unclenches. The body has officially clocked out. What I find fascinating is the interplay between the beta-caryophyllene and the myrcene here — the spicy pepper terpene adds this subtle anti-inflammatory grounding while the myrcene deepens the sedation wave. The floral sweetness from the ocimene and linalool lingers on the palate like a finishing note. This is a textbook indica-dominant experience — euphoric entry, heavy landing. Give yourself nowhere to be tonight.
Effects Profile
Euphoric · Relaxed · Happy
Best enjoyed during night
Deep relaxation and sleep
Best For
Sleep & Bedtime · Watching TV/Movies · Stress Relief
Effect Sources
- 1 Guptilla Weed Strain Information - Leafly leafly.com(opens in new tab)
- 2 Guptilla Weed Strain Information | Weedmaps weedmaps.com(opens in new tab)
- 3 Guptilla Marijuana Strain Information & Reviews - AllBud allbud.com(opens in new tab)
- 4 Guptilla Strain: A Comprehensive Strain Guide - JointCommerce app.jointcommerce.com(opens in new tab)
- 5 Guptilla Strain - Highly Potent and Sedative marijuanabreak.com(opens in new tab)
- 6 GUPTILLA: REG - Colorado Seed Inc. coloradoseedinc.com(opens in new tab)
- 7 Guptilla Feminized Cannabis Seeds | Crop King Seeds cropkingseeds.com(opens in new tab)
- 8 What Strain is Guptilla? Effects & Flavors | The Weed Street Journal – TheWeedStreetJournal theweedstreetjournal.com(opens in new tab)
- 9 Guptilla - Cannabis Popular cannabispopular.com(opens in new tab)
- 10 Guptilla - Fresh Cannabis freshcannabis.co(opens in new tab)
- 11 Guptilla Strain | Marijuana Seeds marijuanaseeds.com(opens in new tab)
- 12 Guptilla Auto pacificseedbank.com(opens in new tab)
- 13 Guptilla Strain - Growing Tips and Medical Effects | Marijuana Guides marijuana-guides.com(opens in new tab)
- 14 Strain Review: Guptilla - DGO Magazine dgomag.com(opens in new tab)
- 15 Guptilla Kush - Maggie's Farm Marijuana Dispensaries maggiesfarmmarijuana.com(opens in new tab)
- 16 Guptilla (Colorado Seed Inc.) :: Cannabis Strain Info - Seedfinder seedfinder.eu(opens in new tab)
- 17 Colorado Seed Company Products | Guptilla | Leafbuyer leafbuyer.com(opens in new tab)
- 18 Guptilla Weed Strain Information | Highburg highburg.ca(opens in new tab)
- 19 Cannabis Strain Review: Guptilla ascendancystrains.com(opens in new tab)
- 20 Guptilla Cannabis Clones – Cloud Genetics cloud-genetics.com(opens in new tab)
- 21 Guptilla | hybrid Weed Strain | Cannapages cannapages.com(opens in new tab)
- 22 Guptilla | THC Classic thcclassic.com(opens in new tab)
22 verified sources
Look, Aroma & Taste
Aroma & Flavor
Diesel · Earthy · Floral
Aroma & Flavor Sources
- 1 Guptilla Weed Strain Information - Leafly leafly.com(opens in new tab)
- 2 Guptilla Weed Strain Information | Weedmaps weedmaps.com(opens in new tab)
- 3 Guptilla Marijuana Strain Information & Reviews - AllBud allbud.com(opens in new tab)
- 4 Guptilla Strain: A Comprehensive Strain Guide - JointCommerce app.jointcommerce.com(opens in new tab)
- 5 Guptilla Strain - Highly Potent and Sedative marijuanabreak.com(opens in new tab)
- 6 GUPTILLA: REG - Colorado Seed Inc. coloradoseedinc.com(opens in new tab)
- 7 Guptilla Feminized Cannabis Seeds | Crop King Seeds cropkingseeds.com(opens in new tab)
- 8 What Strain is Guptilla? Effects & Flavors | The Weed Street Journal – TheWeedStreetJournal theweedstreetjournal.com(opens in new tab)
- 9 Guptilla - Cannabis Popular cannabispopular.com(opens in new tab)
- 10 Guptilla - Fresh Cannabis freshcannabis.co(opens in new tab)
- 11 Guptilla Strain | Marijuana Seeds marijuanaseeds.com(opens in new tab)
- 12 Guptilla Auto pacificseedbank.com(opens in new tab)
- 13 Guptilla Strain - Growing Tips and Medical Effects | Marijuana Guides marijuana-guides.com(opens in new tab)
- 14 Strain Review: Guptilla - DGO Magazine dgomag.com(opens in new tab)
- 15 Guptilla Kush - Maggie's Farm Marijuana Dispensaries maggiesfarmmarijuana.com(opens in new tab)
- 16 Guptilla (Colorado Seed Inc.) :: Cannabis Strain Info - Seedfinder seedfinder.eu(opens in new tab)
- 17 Colorado Seed Company Products | Guptilla | Leafbuyer leafbuyer.com(opens in new tab)
- 18 Guptilla Weed Strain Information | Highburg highburg.ca(opens in new tab)
- 19 Guptilla Cannabis Clones – Cloud Genetics cloud-genetics.com(opens in new tab)
- 20 Guptilla | hybrid Weed Strain | Cannapages cannapages.com(opens in new tab)
- 21 Guptilla | THC Classic thcclassic.com(opens in new tab)
21 verified sources
Aromas
Flavors
Terpene Profile
Limonene leads · 8 terpenes mapped
Terpene Sources
- 1 Guptilla Strain: A Comprehensive Strain Guide - JointCommerce app.jointcommerce.com(opens in new tab)
- 2 What Strain is Guptilla? Effects & Flavors | The Weed Street Journal – TheWeedStreetJournal theweedstreetjournal.com(opens in new tab)
- 3 Guptilla - Cannabis Popular cannabispopular.com(opens in new tab)
- 4 Guptilla - Fresh Cannabis freshcannabis.co(opens in new tab)
- 5 Guptilla Auto pacificseedbank.com(opens in new tab)
- 6 Strain Review: Guptilla - DGO Magazine dgomag.com(opens in new tab)
- 7 Guptilla Kush - Maggie's Farm Marijuana Dispensaries maggiesfarmmarijuana.com(opens in new tab)
- 8 Guptilla Weed Strain Information | Highburg highburg.ca(opens in new tab)
- 9 Cannabis Strain Review: Guptilla ascendancystrains.com(opens in new tab)
- 10 Guptilla Cannabis Clones – Cloud Genetics cloud-genetics.com(opens in new tab)
10 verified sources
Terpene Distribution
Terpene profile: Limonene 0.4%, Caryophyllene 0.3%, Myrcene 0.3%, Pinene 0.2%, Humulene 0.1%, Linalool 0.1%, Ocimene 0.1%, Fenchol 0.1% .
Limonene Dominant
Flavor: Citrus, lemon, orange
Caryophyllene
Flavor: Spicy, peppery, woody
Myrcene
Flavor: Earthy, musky, fruity
Pinene
Flavor: Pine, fresh forest
Humulene
Flavor: Hoppy, woody, earthy
Linalool
Flavor: Floral, lavender, sweet
Ocimene
Flavor: Sweet, herbaceous, woody
Fenchol
Flavor: Fresh, lemon, pine
Full Profile
Limonene
0.4%
Flavor Profile:
Citrus, lemon, orange
Effects:
Caryophyllene
0.31%
Flavor Profile:
Spicy, peppery, woody
Effects:
Myrcene
0.3%
Flavor Profile:
Earthy, musky, fruity
Effects:
Pinene
0.2%
Flavor Profile:
Pine, fresh forest
Effects:
Humulene
0.1%
Flavor Profile:
Hoppy, woody, earthy
Effects:
Linalool
0.1%
Flavor Profile:
Floral, lavender, sweet
Effects:
Ocimene
0.1%
Flavor Profile:
Sweet, herbaceous, woody
Effects:
Fenchol
0.1%
Flavor Profile:
Fresh, lemon, pine
Effects:
Appearance
Deep forest green · Olive green
Color Palette
Texture
Dense, chunky buds with tight structure inherited from GG#4. The surface is heavily coated in a thick blanket of milky white trichomes, giving the buds a frosted, almost silvery appearance. Resin production is exceptionally high, making buds slightly sticky to the touch.
Crystal Density
very high
Exceptional crystal coverage
Chemistry & Research
Medical Effects
8 reported therapeutic uses on file
Medical Effect Sources
- 1 Guptilla Weed Strain Information - Leafly leafly.com(opens in new tab)
- 2 Guptilla Marijuana Strain Information & Reviews - AllBud allbud.com(opens in new tab)
- 3 Guptilla Strain: A Comprehensive Strain Guide - JointCommerce app.jointcommerce.com(opens in new tab)
- 4 Guptilla Strain - Highly Potent and Sedative marijuanabreak.com(opens in new tab)
- 5 Guptilla Feminized Cannabis Seeds | Crop King Seeds cropkingseeds.com(opens in new tab)
- 6 What Strain is Guptilla? Effects & Flavors | The Weed Street Journal – TheWeedStreetJournal theweedstreetjournal.com(opens in new tab)
- 7 Guptilla - Cannabis Popular cannabispopular.com(opens in new tab)
- 8 Guptilla Strain | Marijuana Seeds marijuanaseeds.com(opens in new tab)
- 9 Guptilla Auto pacificseedbank.com(opens in new tab)
- 10 Guptilla Strain - Growing Tips and Medical Effects | Marijuana Guides marijuana-guides.com(opens in new tab)
- 11 Guptilla Kush - Maggie's Farm Marijuana Dispensaries maggiesfarmmarijuana.com(opens in new tab)
- 12 Guptilla Weed Strain Information | Highburg highburg.ca(opens in new tab)
- 13 Guptilla Cannabis Clones – Cloud Genetics cloud-genetics.com(opens in new tab)
13 verified sources
Mental Effects
- •Anxiety Relief
Reduces anxiety and promotes calm relaxation
- •Stress Reduction
Alleviates stress and tension without excessive sedation
- •Depression Management
Enhances mood and alleviates depressive symptoms
- •Focus Enhancement
Improves mental clarity and concentration levels
Professor High visualization
Body Effects
- •Pain Management
Reduces chronic pain and muscle tension effectively
- •Insomnia Relief
Promotes deep sleep and addresses sleeping disorders
- •Muscle Relaxation
Eases muscle spasms and promotes physical relaxation
- •Inflammation Reduction
Decreases inflammation throughout the body
Medical Disclaimer: This information is AI-generated based on available research and user reports, provided for educational purposes only, and is not intended as medical advice. Cannabis affects everyone differently. Consult with a qualified healthcare professional before using cannabis for medical purposes. Do not use cannabis if pregnant, nursing, or have a medical condition without consulting your doctor.
What Research Says
Peer-reviewed studies, terpene science & safety guidance
What does the research say about Guptilla?
Guptilla is a hybrid cannabis strain containing up to 29.0% THC, with a terpene profile dominated by Limonene and Caryophyllene. This page currently has good data confidence. Below are profile sources when available plus authoritative resources for understanding the compounds in this strain.
Terpene Research
Cannabinoid Information
Cannabis Regulations & Safety
Educational resources only — not medical advice. Always consult a qualified clinician for health decisions.
Cannabinoids (THC & CBD)
THC 18-29% · Type I chemovar
THC% tells you how strong. Terpenes tell you how it feels.
THC percentage is a property of the product in your hand, not of the strain. It shifts with the batch, the grower, the harvest, and how the flower was cured and stored — the same strain can test several points apart from two different jars.
Treat the ranges below as market context for what to expect on a shelf — then read the actual label on the product you are buying, and use the terpene profile to judge how it will feel.
High THC (>15%), low CBD (<1%) - Most common recreational strains
Using It Well
Consumption Methods
Smoking · Vaping · Edibles
Recommended Methods
Side Effects
Dry Mouth · Dry Eyes · +3 more
Side effects vary by individual. Start low, go slow. Consult a healthcare professional with concerns.
These are commonly reported effects. Individual experiences may vary based on dosage, tolerance, and consumption method.
Where It Comes From
Lineage & History
Gorilla Glue #4 × Gupta Kush · bred by Colorado Seed Inc.
Lineage Sources
- 1 Guptilla Weed Strain Information - Leafly leafly.com(opens in new tab)
- 2 Guptilla Weed Strain Information | Weedmaps weedmaps.com(opens in new tab)
- 3 Guptilla Marijuana Strain Information & Reviews - AllBud allbud.com(opens in new tab)
- 4 Guptilla Strain: A Comprehensive Strain Guide - JointCommerce app.jointcommerce.com(opens in new tab)
- 5 Guptilla Strain - Highly Potent and Sedative marijuanabreak.com(opens in new tab)
- 6 GUPTILLA: REG - Colorado Seed Inc. coloradoseedinc.com(opens in new tab)
- 7 Guptilla Feminized Cannabis Seeds | Crop King Seeds cropkingseeds.com(opens in new tab)
- 8 What Strain is Guptilla? Effects & Flavors | The Weed Street Journal – TheWeedStreetJournal theweedstreetjournal.com(opens in new tab)
- 9 Guptilla - Cannabis Popular cannabispopular.com(opens in new tab)
- 10 Guptilla - Fresh Cannabis freshcannabis.co(opens in new tab)
- 11 Guptilla Strain | Marijuana Seeds marijuanaseeds.com(opens in new tab)
- 12 Guptilla Auto pacificseedbank.com(opens in new tab)
- 13 Guptilla Strain - Growing Tips and Medical Effects | Marijuana Guides marijuana-guides.com(opens in new tab)
- 14 Strain Review: Guptilla - DGO Magazine dgomag.com(opens in new tab)
- 15 Guptilla Kush - Maggie's Farm Marijuana Dispensaries maggiesfarmmarijuana.com(opens in new tab)
- 16 Guptilla (Colorado Seed Inc.) :: Cannabis Strain Info - Seedfinder seedfinder.eu(opens in new tab)
- 17 Colorado Seed Company Products | Guptilla | Leafbuyer leafbuyer.com(opens in new tab)
- 18 Guptilla Weed Strain Information | Highburg highburg.ca(opens in new tab)
- 19 Guptilla Cannabis Clones – Cloud Genetics cloud-genetics.com(opens in new tab)
- 20 Guptilla | hybrid Weed Strain | Cannapages cannapages.com(opens in new tab)
- 21 Guptilla | THC Classic thcclassic.com(opens in new tab)
21 verified sources
Indica-dominant hybrid created by crossing Gorilla Glue #4 with Gupta Kush, resulting in a potent strain with balanced effects
Genetics
Origin Timeline
First cultivated in 2019
Breeder
Colorado Seed Inc.
Seed Bank
Colorado Seed Inc.
The Full Story
Detailed Description
The long-form profile · ~4 min read
Guptilla: The Gorilla Kush Powerhouse
Guptilla is an indica-dominant hybrid (70% Indica / 30% Sativa) that earns its formidable reputation through sheer potency and a remarkably complex sensory profile. Born from the crossbreeding of two legendary strains, Guptilla delivers a deeply satisfying experience that balances cerebral euphoria with full-body relaxation — making it a go-to choice for experienced consumers seeking both mental uplift and physical relief.
🧬 Genetic Heritage & Lineage
Breeder: Colorado Seed Inc.
Year Created: ~2019
Parent Strains: Gorilla Glue #4 × Gupta Kush
Guptilla inherits the best of both worlds. Gorilla Glue #4 — one of the most decorated and sought-after strains of the modern era — contributes its signature resin-drenched density, potent THC levels, and that unmistakable fuel-and-chocolate aroma. Gupta Kush, a lesser-known but deeply Kush-rooted variety, brings floral complexity, earthy depth, and the body-melting indica sedation that makes Guptilla so effective at unwinding tension. Colorado Seed Inc., known for their commitment to craft genetics, refined this cross into a stable, widely available cultivar that has gained recognition across dispensaries in Colorado and beyond.
👃 Terpene Profile & Aromatics
Guptilla's terpene profile is rich and multidimensional, with a total terpene content of ~2.31% — well above average for a modern hybrid.
| Terpene | % | Effect Contribution |
|---|---|---|
| Limonene | 0.40% | Mood elevation, anxiety relief |
| beta-Caryophyllene | 0.31% | Pain relief, anti-inflammatory |
| Myrcene | 0.30% | Sedation, body relaxation |
| alpha-Pinene | 0.10% | Mental alertness, focus |
| Linalool | 0.10% | Calming, sleep support |
| Humulene | 0.10% | Anti-inflammatory |
| Ocimene | 0.10% | Uplifting, sweet floral notes |
When you open a jar of Guptilla, you're immediately hit with a pungent, skunky diesel blast — a clear nod to its GG#4 lineage. Underneath that opening punch, you'll detect layers of earthy Kush funk, bright citrus lemon zest (courtesy of limonene), sweet floral notes from ocimene and linalool, and a deep pine-wood undertone from pinene. There's even a subtle peppery spice from caryophyllene that rounds out the aromatic complexity beautifully.
👅 Flavor Experience
The flavor journey of Guptilla is as layered as its aroma. On the initial inhale, you'll taste sweet grape and citrus upfront — almost candy-like but grounded by earthy Kush. The mid-palate introduces diesel and pine with a spicy peppery kick from beta-caryophyllene. On the exhale, you may notice rich chocolate and sweet earth lingering on the tongue, with a faint floral aftertaste that coats the palate pleasantly. Whether smoked or vaped, the flavor profile rewards slow, deliberate consumption.
🎯 Effects & Experience
Guptilla's THC content ranges from 18–29%, making it best suited for intermediate to experienced consumers. The high arrives with notable speed:
- Onset (0–5 min): A wave of cerebral euphoria lifts the mood immediately — you'll feel a genuine happiness and sense of mental uplift driven by limonene
- Peak (15–45 min): The indica foundation rolls in, delivering deep physical relaxation and sedation. Muscles ease, tension dissolves, and a pleasant body heaviness sets in
- Duration: Typically 2–3 hours, fading gently into a deeply sleepy, sedated state
- The sativa component contributes a focused, uplifted quality early on before the indica takes over
👁️ Visual Characteristics
Guptilla buds are visually impressive — dense and chunky with the structural hallmarks of its GG#4 heritage. You'll notice:
- Deep forest green to olive green coloring throughout
- Rich orange-amber pistils weaving through the bud surface
- An extraordinary blanket of white trichomes that gives buds a frosted, almost silver appearance — indicative of its high THC ceiling
- Occasional purple undertones in cooler-grown phenotypes
💚 Medical & Therapeutic Potential
Guptilla's terpene synergy and potency make it well-suited for therapeutic use. It may help with:
- Insomnia — myrcene + linalool combination promotes deep, restorative sleep
- Chronic pain & inflammation — beta-caryophyllene and humulene target CB2 receptors for physical relief
- Anxiety & stress — limonene's mood-lifting properties provide mental calm
- Muscle spasms — body-relaxing indica genetics ease physical tension
- Depression — euphoric, mood-enhancing onset may lift low moods
⚠️ Consumer Considerations
Guptilla is best enjoyed in the evening or nighttime hours given its sedating indica dominance. If you're new to cannabis or have a lower THC tolerance, approach this strain with respect — start with a single hit and wait to assess effects before consuming more. Dry mouth is the most commonly reported side effect, so keep water nearby. This strain shines brightest when you have no obligations ahead and can fully surrender to its relaxing embrace.
Research Methodology
How we compiled this strain profile
This strain profile was compiled from 25 published sources covering 'Guptilla'. Our research pipeline cross-references these sources and reports how strongly they agree — see the confidence breakdown below.
Data Quality by Section
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Strain Highlights
Key insights at a glance
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