67 studies

Cannabis and Epilepsy Research

Studies on CBD and cannabis for seizure disorders, from the trials behind Epidiolex to ongoing work on other epilepsies.

Latest Epilepsy studies

Thumbnail for research paper: Long-term CBD seizure response did not differ by genetic status in LGS
Research
Yesterday

Long-term CBD seizure response did not differ by genetic status in LGS

CBD Epilepsy
Read Summary of Long-term CBD seizure response did not differ by genetic status in LGS
Thumbnail for research paper: Rat study finds CBD and THC effects on seizure-related oxygen loss vary
Research
1 weeks ago

Rat study finds CBD and THC effects on seizure-related oxygen loss vary

CBD THC Epilepsy
Read Summary of Rat study finds CBD and THC effects on seizure-related oxygen loss vary
Thumbnail for research paper: THC use in youth remains uncertain as long-term safety evidence is limited
Research
2 weeks ago

THC use in youth remains uncertain as long-term safety evidence is limited

THC CBD Mental Health
Read Summary of THC use in youth remains uncertain as long-term safety evidence is limited
Thumbnail for research paper: In Lafora disease mice, CBD and D2 activation restored striatal plasticity
Research
2 weeks ago

In Lafora disease mice, CBD and D2 activation restored striatal plasticity

CBD Epilepsy Endocannabinoid
Read Summary of In Lafora disease mice, CBD and D2 activation restored striatal plasticity
Thumbnail for research paper: Review describes AHC and reports cannabidiol as an additional treatment option
Research
3 weeks ago

Review describes AHC and reports cannabidiol as an additional treatment option

CBD Epilepsy Mental Health
Read Summary of Review describes AHC and reports cannabidiol as an additional treatment option
Thumbnail for research paper: In mice, THC lowered observed seizure severity but caused marked sedation
Research
3 weeks ago

In mice, THC lowered observed seizure severity but caused marked sedation

THC CBD Epilepsy
Read Summary of In mice, THC lowered observed seizure severity but caused marked sedation
Thumbnail for research paper: Review finds promise in acidic cannabinoids, but human benefits remain unproven
Review
Oct 2026

Review finds promise in acidic cannabinoids, but human benefits remain unproven

THC CBD Epilepsy
Read Summary of Review finds promise in acidic cannabinoids, but human benefits remain unproven
Thumbnail for research paper: Long-term records link adjunctive CBD with fewer seizures in adults with LGS
Research
Oct 2026

Long-term records link adjunctive CBD with fewer seizures in adults with LGS

CBD Epilepsy
Read Summary of Long-term records link adjunctive CBD with fewer seizures in adults with LGS
Thumbnail for research paper: Retrospective study links add-on CBD with sustained seizure reduction in…
Research
Sep 2026

Retrospective study links add-on CBD with sustained seizure reduction in…

CBD Epilepsy
Read Summary of Retrospective study links add-on CBD with sustained seizure reduction in…
Thumbnail for research paper: Frequent cannabis use linked to greater seizure burden in epilepsy
Research
Sep 2026

Frequent cannabis use linked to greater seizure burden in epilepsy

Epilepsy
Read Summary of Frequent cannabis use linked to greater seizure burden in epilepsy
Thumbnail for research paper: Review finds promising but variable CBD evidence in dogs and cats
Review
Sep 2026

Review finds promising but variable CBD evidence in dogs and cats

CBD Pain Epilepsy
Read Summary of Review finds promising but variable CBD evidence in dogs and cats
Thumbnail for research paper: CBD in adults with rare epilepsies: real-world results
Research
Sep 2026

CBD in adults with rare epilepsies: real-world results

CBD Epilepsy
Read Summary of CBD in adults with rare epilepsies: real-world results
Thumbnail for research paper: Review maps epilepsy treatments, including cannabidiol, and genetics
Review
Sep 2026

Review maps epilepsy treatments, including cannabidiol, and genetics

CBD Epilepsy
Read Summary of Review maps epilepsy treatments, including cannabidiol, and genetics
Thumbnail for research paper: Intranasal NLC-CBD shows promise, but clinical trials are still needed
Review
Sep 2026

Intranasal NLC-CBD shows promise, but clinical trials are still needed

CBD Epilepsy
Read Summary of Intranasal NLC-CBD shows promise, but clinical trials are still needed
Thumbnail for research paper: Lab study links CYP3A4 inhibition to altered CBD metabolism
Research
Sep 2026

Lab study links CYP3A4 inhibition to altered CBD metabolism

CBD Epilepsy
Read Summary of Lab study links CYP3A4 inhibition to altered CBD metabolism
Thumbnail for research paper: Review finds newer antiseizure drugs generally spare cognition
Review
Sep 2026

Review finds newer antiseizure drugs generally spare cognition

CBD Epilepsy
Read Summary of Review finds newer antiseizure drugs generally spare cognition
Thumbnail for research paper: Where cannabis helpsβ€”and where the evidence remains uncertain
Research
Sep 2026

Where cannabis helpsβ€”and where the evidence remains uncertain

CBD Pain Epilepsy
Read Summary of Where cannabis helpsβ€”and where the evidence remains uncertain
Thumbnail for research paper: Retrospective review finds similar CBD response across pediatric epilepsy…
Research
Aug 2026

Retrospective review finds similar CBD response across pediatric epilepsy…

CBD Epilepsy
Read Summary of Retrospective review finds similar CBD response across pediatric epilepsy…
Thumbnail for research paper: Could CBD offer a safer path for psychosis treatment?
Review
Aug 2026

Could CBD offer a safer path for psychosis treatment?

CBD THC Mental Health
Read Summary of Could CBD offer a safer path for psychosis treatment?
Thumbnail for research paper: How kidney and liver health can change CBD seizure-medication dosing
Review
Aug 2026

How kidney and liver health can change CBD seizure-medication dosing

CBD Epilepsy
Read Summary of How kidney and liver health can change CBD seizure-medication dosing
Thumbnail for research paper: How patients use medical cannabis alongside seizure medicines
Research
Aug 2026

How patients use medical cannabis alongside seizure medicines

CBD THC Epilepsy
Read Summary of How patients use medical cannabis alongside seizure medicines
Thumbnail for research paper: Real-world Dravet cohort links FFA to fewer status episodes
Research
Aug 2026

Real-world Dravet cohort links FFA to fewer status episodes

CBD Epilepsy
Read Summary of Real-world Dravet cohort links FFA to fewer status episodes
Thumbnail for research paper: Caregivers offer new insight into epilepsy trial participation
Research
Aug 2026

Caregivers offer new insight into epilepsy trial participation

CBD Epilepsy
Read Summary of Caregivers offer new insight into epilepsy trial participation
Thumbnail for research paper: CBD shows stronger seizure protection with repeated treatment
Research
Aug 2026

CBD shows stronger seizure protection with repeated treatment

CBD Epilepsy Neuroprotection
Read Summary of CBD shows stronger seizure protection with repeated treatment
Thumbnail for research paper: CBD shows promise, but stronger clinical evidence is still needed
Review
Aug 2026

CBD shows promise, but stronger clinical evidence is still needed

CBD Anxiety Epilepsy
Read Summary of CBD shows promise, but stronger clinical evidence is still needed
Thumbnail for research paper: CBD protects memory as seizures worsen in a rat epilepsy model
Research
Jul 2026

CBD protects memory as seizures worsen in a rat epilepsy model

CBD Epilepsy Neuroprotection
Read Summary of CBD protects memory as seizures worsen in a rat epilepsy model
Thumbnail for research paper: Cannabidiol curbs seizures in a mouse model of rare disease
Research
Jul 2026

Cannabidiol curbs seizures in a mouse model of rare disease

CBD Epilepsy Neuroprotection
Read Summary of Cannabidiol curbs seizures in a mouse model of rare disease
Thumbnail for research paper: CBD may improve more than seizures in hard-to-treat epilepsy
Review
Jul 2026

CBD may improve more than seizures in hard-to-treat epilepsy

CBD Epilepsy Mental Health
Read Summary of CBD may improve more than seizures in hard-to-treat epilepsy
Thumbnail for research paper: How community input shaped a CBD trial for TSC-related epilepsy
Research
Jul 2026

How community input shaped a CBD trial for TSC-related epilepsy

CBD Epilepsy
Read Summary of How community input shaped a CBD trial for TSC-related epilepsy
Thumbnail for research paper: Preclinical CB2R compounds show anticonvulsant activity in animals
Research
Jul 2026

Preclinical CB2R compounds show anticonvulsant activity in animals

Epilepsy Endocannabinoid
Read Summary of Preclinical CB2R compounds show anticonvulsant activity in animals
Thumbnail for research paper: Cannabis shows strong seizure-control promise in real-world epilepsy treatment
Research
Jul 2026

Cannabis shows strong seizure-control promise in real-world epilepsy treatment

Epilepsy CBD THC
Read Summary of Cannabis shows strong seizure-control promise in real-world epilepsy treatment
Thumbnail for research paper: How neurologists' knowledge gaps may limit treatment options for epilepsy
Research
Jul 2026

How neurologists' knowledge gaps may limit treatment options for epilepsy

Epilepsy
Read Summary of How neurologists' knowledge gaps may limit treatment options for epilepsy
Thumbnail for research paper: RNA fragments hold seizure secrets and link to cannabis receptors
Research
Jun 2026

RNA fragments hold seizure secrets and link to cannabis receptors

Epilepsy Neuroprotection Endocannabinoid
Read Summary of RNA fragments hold seizure secrets and link to cannabis receptors
Thumbnail for research paper: CBD and epilepsy: promise tempered by safety and evidence gaps
Review
Jun 2026

CBD and epilepsy: promise tempered by safety and evidence gaps

CBD Epilepsy Neuroprotection
Read Summary of CBD and epilepsy: promise tempered by safety and evidence gaps
Thumbnail for research paper: CBD nanoemulsion reverses drug-induced reproductive damage
Research
Jun 2026

CBD nanoemulsion reverses drug-induced reproductive damage

CBD Epilepsy Endocannabinoid
Read Summary of CBD nanoemulsion reverses drug-induced reproductive damage
Thumbnail for research paper: Cannabinoids show promise for autism and seizure disorders in children, but more research needed
Review
Jun 2026

Cannabinoids show promise for autism and seizure disorders in children, but more research needed

Neuroprotection Epilepsy Mental Health
Read Summary of Cannabinoids show promise for autism and seizure disorders in children, but more research needed
Thumbnail for research paper: CBDA extract may strengthen cannabis effects on seizure-related channels
Research
Jun 2026

CBDA extract may strengthen cannabis effects on seizure-related channels

CBD Epilepsy
Read Summary of CBDA extract may strengthen cannabis effects on seizure-related channels
Thumbnail for research paper: CBD works best as preventive epilepsy treatment, not after seizures start
Research
Jun 2026

CBD works best as preventive epilepsy treatment, not after seizures start

Epilepsy Neuroprotection Endocannabinoid
Read Summary of CBD works best as preventive epilepsy treatment, not after seizures start
Thumbnail for research paper: Fenfluramine use linked to fewer seizure-related healthcare visits
Research
Jun 2026

Fenfluramine use linked to fewer seizure-related healthcare visits

Epilepsy CBD
Read Summary of Fenfluramine use linked to fewer seizure-related healthcare visits
Thumbnail for research paper: How seizures fuel cognitive decline and addiction risk
Review
Jun 2026

How seizures fuel cognitive decline and addiction risk

Epilepsy Addiction Neuroprotection
Read Summary of How seizures fuel cognitive decline and addiction risk
Thumbnail for research paper: Minor cannabinoid shows promise as measles virus fighter
Research
Jun 2026

Minor cannabinoid shows promise as measles virus fighter

Epilepsy Neuroprotection
Read Summary of Minor cannabinoid shows promise as measles virus fighter
Thumbnail for research paper: CBD shows promise in breakthrough Lennox-Gastaut syndrome model
Research
Jun 2026

CBD shows promise in breakthrough Lennox-Gastaut syndrome model

Epilepsy CBD Neuroprotection
Read Summary of CBD shows promise in breakthrough Lennox-Gastaut syndrome model
Thumbnail for research paper: CBD restores sleep and reduces seizures in Angelman syndrome
Research
Jun 2026

CBD restores sleep and reduces seizures in Angelman syndrome

Sleep Epilepsy CBD
Read Summary of CBD restores sleep and reduces seizures in Angelman syndrome
Thumbnail for research paper: Beyond seizures: Comprehensive care approach for Lennox-Gastaut syndrome
Review
Jun 2026

Beyond seizures: Comprehensive care approach for Lennox-Gastaut syndrome

Epilepsy Neuroprotection
Read Summary of Beyond seizures: Comprehensive care approach for Lennox-Gastaut syndrome
Thumbnail for research paper: THC doubles seizure risk in emergency cases, study confirms
Research
Jun 2026

THC doubles seizure risk in emergency cases, study confirms

Epilepsy Neuroprotection
Read Summary of THC doubles seizure risk in emergency cases, study confirms
Thumbnail for research paper: Boosting brain's natural cannabinoids stops seizure damage in mice
Research
May 2026

Boosting brain's natural cannabinoids stops seizure damage in mice

Epilepsy Endocannabinoid Neuroprotection
Read Summary of Boosting brain's natural cannabinoids stops seizure damage in mice
Thumbnail for research paper: CBD shows promise in treatment-resistant chromosome 15 epilepsy
Research
May 2026

CBD shows promise in treatment-resistant chromosome 15 epilepsy

Epilepsy Neuroprotection
Read Summary of CBD shows promise in treatment-resistant chromosome 15 epilepsy
Thumbnail for research paper: Cannabidiol Use in Developmental and Epileptic Encephalopathies: A Syndrome- and Age-Stratified Systematic Review and Meta-analysis.
Review
May 2026

Cannabidiol Use in Developmental and Epileptic Encephalopathies: A Syndrome- and Age-Stratified Systematic Review and Meta-analysis.

Epilepsy CBD
Read Summary of Cannabidiol Use in Developmental and Epileptic Encephalopathies: A Syndrome- and Age-Stratified Systematic Review and Meta-analysis.

See all 67 Epilepsy studies β†’

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