Research — page 2

Geneticists have sequenced commercial cannabis for a decade. Same name, different plant is normal. Here's what DNA testing can and can't tell you.

A 277-product Colorado study found 96% of concentrate labels accurate but only 57% of flower labels. Both skewed lower than printed. Here's why.

A 256-nucleotide strand of RNA is stunting cannabis plants and thinning their trichomes—usually with no visible symptoms until harvest.

Anthocyanins make cannabis purple — the same pigments as blueberries and red cabbage. The real chemistry, and why purple never meant potent.

GABA is your brain's brake pedal. How cannabis modulates it through retrograde signaling, why THC dose flips calm into anxiety, and what terpenes do.

Glutamate is the brain's main excitatory signal. How cannabis CB1 receptors suppress its release, and why that matters for memory and neuroprotection.

Cannabis and psychedelics share surprising biology. Explore CB1 and 5-HT2A cross-talk, co-use science, and harm reduction with Professor High.

Why a reliable THC breathalyzer is so hard to build: the science of cannabis impairment, blood and breath testing, and where roadside tech stands in 2026.

CBDA vs CBD compared: how heat decarboxylates raw cannabis, why acidic CBDA targets 5-HT1A and COX-2, and what activation changes for your goals.

CBE (cannabielsoin) is a CBD oxidation product and minor metabolite with almost no human data. Here's the candid science and why it matters.

CBL (cannabicyclol) is cannabis's rarest cannabinoid: a light-made degradation product of CBC with almost no research. Here's what we actually know.

CBT (cannabitriol) is a rare oxidation product of THC with almost no human research. Here's the candid science, and why product claims outrun the data.

Endocannabinoids are built from the fats you eat. Here is the real science on how omega-3s, black pepper, and exercise shape your body's cannabinoid tone.

Psilocybin mushrooms and cannabis act on different receptors. Professor High breaks down the co-use science, risks, and harm reduction.

How adenosine builds sleep pressure, why caffeine blocks it, and where cannabinoids like CBD may touch this pathway. The science, hedged honestly.

Can cannabis pair with ice baths, saunas, and contrast therapy? The thin science, the endocannabinoid overlap, and the real safety risks—explained.

An honest, balanced look at the science on cannabis and dementia: agitation and appetite trials, neuroprotection research, and real cognition concerns.

How cannabis fits into HIV/AIDS care — wasting, neuropathic pain, nausea, immune effects, and the antiretroviral drug-interaction caution.

THC may lower sperm count, motility, and morphology, and the data leans toward caution. Here's what the fertility research actually shows.

Does the MTHFR gene change how cannabis hits you? We separate the real genetics of THC metabolism from the methylation myths circulating online.

An honest look at cannabis and CBD for osteoarthritis: strong animal data, limited human evidence, and what the joint-pain research actually says.

What the research really shows about cannabis for perimenopause symptoms like sleep, mood, and hot flashes during the hormone transition years.

An honest look at the early research on cannabis for sickle cell disease pain — the one small RCT, self-medication surveys, and key cautions.

How cannabinoids talk to your vagus nerve and gut-brain axis — the science of CB1 on vagal afferents, nausea, appetite, motility, and mood.